Question 1

Drug susceptibility testing

Accepted Answer

A)  determines the patient's response to various antimicrobics.
B)  determines the pathogen's response to various antimicrobics.
C)  determines if normal flora will be affected by antimicrobics.
D)  determines if the drug is increasing to toxic levels in a patient.
E)  determines the pathogen's identity.F) A) and D)
G) All of the above

Question 2

The drug used for several protozoan infections is

Accepted Answer

A)  nystatin.
B)  griseofulvin.
C)  amphotericin B.
D)  sulfa drugs.
E)  metronidazole.F) B) and D)
G) A) and E)

Question 3

There are fewer antifungal, antiprotozoan, and antihelminth drugs compared to antibacterial drugs because these organisms

Accepted Answer

A)  do not cause many human infections.
B)  are not affected by antimicrobics.
C)  are so similar to human cells that selective drug toxicity is difficult to achieve.
D)  are parasites found inside human cells.
E)  have fewer target sites compared to bacteria.F) B) and C)
G) A) and B)

Question 4

Resistance factor plasmids are transferred to other bacterial cells during transformation, transduction, and conjugation.

Accepted Answer

A) True 
 B)False

Question 5

The macrolide, __________, is a useful substitute for dealing with penicillin-resistant Streptococci.

Accepted Answer

The answer of The macrolide, __________, is a useful substitute...

Question 6

Which is the best guide for selecting an effective antibiotic?

Accepted Answer

A)  results of antimicrobial susceptibility testing
B)  identification of the microbe causing the infection
C)  history of prior antibiotics prescribed for the patient
D)  location of the patient's infectionE) B) and C)
F) A) and B)

Question 7

Acyclovir is used to treat

Accepted Answer

A)  influenza A virus.
B)  HIV.
C)  shingles, chickenpox, and genital herpes.
D)  respiratory syncytial virus.
E)  hepatitis C virus.F) B) and C)
G) A) and E)

Question 8

A ratio of the dose of the drug that is toxic to humans versus the minimum effective dose for that pathogen is assessed to predict the potential for toxic drug reactions.This is called the

Accepted Answer

A)  Kirby-Bauer technique.
B)  antibiogram.
C)  E-test.
D)  minimum inhibitory concentration (MI
C)  .
E)  therapeutic index (TI) .F) C) and E)
G) A) and B)

Question 9

The drug used against intestinal anaerobic bacteria, that can also alter normal flora causing antibiotic-associated colitis is

Accepted Answer

A)  chloramphenicol.
B)  clindamycin.
C)  ciprofloxacin.
D)  bacitracin.
E)  gentamicin.F) C) and E)
G) B) and D)

Question 10

All of the following pertain to cephalosporins except

Accepted Answer

A)  they have a beta-lactam ring.
B)  greater resistance to beta-lactamases.
C)  newer generations have activity against gram negatives.
D)  many administered by injection not orally.
E)  they are synthetic drugs.F) B) and C)
G) A) and E)

Question 11

All of the following could be reasons why antimicrobic treatment fails except

Accepted Answer

A)  the inability of the drug to diffuse into the infected body compartment.
B)  a mixed infection where some of the pathogens are drug resistant.
C)  not completing the full course of treatment.
D)  a disk diffusion test showing pathogen sensitivity to the antimicrobic.
E)  diminished gastrointestinal absorption due to an underlying condition or age.F) C) and D)
G) A) and B)

Question 12

Janice has just had hip replacement surgery and her physician has prescribed antibiotics and directed her to take them every time she has a dental appointment.This is an example of antibiotic

Accepted Answer

A)  synergy.
B)  prophylaxis.
C)  allergy.
D)  abuse.E) C) and D)
F) B) and D)

Question 13

All of the following pertain to fluoroquinolones except

Accepted Answer

A)  they are broad spectrum.
B)  they include ciprofloxacin and levofloxacin.
C)  they are nephrotoxic.
D)  they are used to treat respiratory, urinary, and sexually-transmitted infections.
E)  they work by inhibiting bacterial DNA replication.F) A) and D)
G) A) and E)

Question 14

Antibiotics are derived from all the following except

Accepted Answer

A)  Penicillium.
B)  Bacillus.
C)  Staphylococcus.
D)  Streptomyces.
E)  Cephalosporium.F) B) and D)
G) B) and C)

Question 15

Which of these drugs is used to treat cases of tuberculosis?

Accepted Answer

A)  penicillin G.
B)  vancomycin.
C)  aminoglycosides.
D)  synercid.
E)  isoniazid.F) A) and B)
G) D) and E)

Question 16

Drugs that are hepatotoxic cause damage to a patient's kidneys.

Accepted Answer

A) True 
 B)False

Question 17

Which antimicrobic does not interfere with protein synthesis?

Accepted Answer

A)  aminoglycosides
B)  tetracyclines
C)  erythromycin
D)  trimethroprim
E)  chloramphenicolF) B) and C)
G) A) and B)

Question 18

Discuss the problems with development of antifungal, antiprotozoan, antihelminth, and antiviral drugs compared to the antibacterial drugs.Discuss at least 3 different modes of action that have been developed for these drugs.

Accepted Answer

The development of antifungal, antiproto...

Question 19

The development of successful antiviral drugs has been relatively easy because viral structure is so different from the structure of eukaryotic cells.

Accepted Answer

A) True 
 B)False

Question 20

Species of Bacillus produce bacitracin and the polymyxins.

Accepted Answer

A) True 
 B)False

Exam 12: Drugs, Microbes, Host--The Elements of Chemotherapy

Resistance factor plasmids are transferred to other bacterial cells during transformation, transduction, and conjugation.

Correct AnswerverifiedShow Answer

The development of successful antiviral drugs has been relatively easy because viral structure is so different from the structure of eukaryotic cells.

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All of the following pertain to fluoroquinolones except

Correct AnswerverifiedShow Answer

A ratio of the dose of the drug that is toxic to humans versus the minimum effective dose for that pathogen is assessed to predict the potential for toxic drug reactions.This is called the

Correct AnswerverifiedShow Answer

The drug used against intestinal anaerobic bacteria, that can also alter normal flora causing antibiotic-associated colitis is

Correct AnswerverifiedShow Answer

Discuss the problems with development of antifungal, antiprotozoan, antihelminth, and antiviral drugs compared to the antibacterial drugs.Discuss at least 3 different modes of action that have been developed for these drugs.

Correct AnswerAnswered by ExamLex AIThe development of antifungal, antiproto...View AnswerShow Answer

Acyclovir is used to treat

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Which of these drugs is used to treat cases of tuberculosis?

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Which antimicrobic does not interfere with protein synthesis?

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The drug used for several protozoan infections is

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All of the following pertain to cephalosporins except

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Antibiotics are derived from all the following except

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There are fewer antifungal, antiprotozoan, and antihelminth drugs compared to antibacterial drugs because these organisms

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Janice has just had hip replacement surgery and her physician has prescribed antibiotics and directed her to take them every time she has a dental appointment.This is an example of antibiotic

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The macrolide, __________, is a useful substitute for dealing with penicillin-resistant Streptococci.

Correct AnswerverifiedShow Answer

Drug susceptibility testing

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Species of Bacillus produce bacitracin and the polymyxins.

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All of the following could be reasons why antimicrobic treatment fails except

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Which is the best guide for selecting an effective antibiotic?

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Drugs that are hepatotoxic cause damage to a patient's kidneys.

Correct AnswerverifiedShow Answer

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The development of antifungal, antiproto...
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