Question 1

What type of cells secrete antibodies?

Accepted Answer

A)  memory B cells
B)  cytotoxic T cells
C)  plasma cells
D)  helper T cells
E)  antigen-presenting cellsF) A) and D)
G) B) and C)

Question 2

Which of the following is a special binding substance that enhances immunogenicity and prolongs antigen retention at the injection site?

Accepted Answer

A)  adjuvant
B)  booster
C)  antibodies to toxin
D)  gamma globulin
E)  "Trojan horse" recombinant vaccineF) A) and E)
G) A) and D)

Question 3

High titers of specific antibodies are characteristic of

Accepted Answer

A)  specific immune globulin (SIG) .
B)  gamma globulin.
C)  immune serum globulin (ISG) .
D)  attenuated vaccines.
E)  toxoids.F) A) and B)
G) C) and D)

Question 4

Class II MHC genes code for

Accepted Answer

A)  certain secreted complement components.
B)  self receptors recognized by T lymphocytes.
C)  all HLA antigens.
D)  receptors located primarily on macrophages and B cells.
E)  All of the choices are correct.F) All of the above
G) B) and D)

Question 5

Which of the following is not a target for TC cells?

Accepted Answer

A)  bacteria
B)  virus-infected cells
C)  cancer cells
D)  human transplanted liver
E)  pig transplanted heartF) A) and B)
G) A) and C)

Question 6

Antigens that elicit allergic reactions are called

Accepted Answer

A)  superantigens.
B)  heterophilic antigens.
C)  allergens.
D)  autoantigens.E) A) and B)
F) A) and C)

Question 7

All nucleated cells contain

Accepted Answer

A)  class I MHC.
B)  class II MHC.
C)  secretory antibodies.
D)  IgE receptors.
E)  IgD receptors.F) D) and E)
G) B) and C)

Question 8

The most significant cells in graft rejection are

Accepted Answer

A)  helper T cells.
B)  suppressor T cells.
C)  cytotoxic T cells.
D)  delayed hypersensitivity T cells.
E)  natural killer (NK) cells.F) B) and E)
G) A) and B)

Question 9

Lymphocyte maturation involves

Accepted Answer

A)  hormonal signals that initiate development.
B)  B cells maturing in bone marrow sites.
C)  T cells maturing in the thymus.
D)  release of mature lymphocytes to begin migration to various lymphoid organs.
E)  All of the choices are correct.F) A) and B)
G) A) and C)

Question 10

Each _____ fragment of an antibody molecule contains the variable regions of a heavy and light chain that folds into a groove for one epitope.

Accepted Answer

A)  variable
B)  FAb
C)  Fc
D)  terminal
E)  hingeF) B) and C)
G) A) and B)

Question 11

A patient enters your clinic with a suspected helminthic infection.In support of this diagnosis,you suspect elevated levels of which antibody in the patient's serum?

Accepted Answer

A)  IgD
B)  IgE
C)  IgG
D)  IgME) A) and B)
F) B) and C)

Question 12

Properties of effective antigens include all of the following except

Accepted Answer

A)  foreign to the immune system.
B)  molecular complexity.
C)  large molecules with a minimum molecular weight of 1,000.
D)  large polymers made up of repeating subunits.
E)  cells or large,complex molecules.F) A) and B)
G) D) and E)

Question 13

You do not really want to get your 3 children vaccinated.Your view is why do it,when others around you will get the vaccine and end up protecting you and your children.Which is an accurate statement that your physician may provide to you in response to your challenge to vaccination?

Accepted Answer

A)  Your choice is fine,your children will never become infected since this is actually the basis of herd immunity.
B)  This is not a smart choice.If enough people choose not to get vaccinated,the susceptible population grows to a large size breaking the protective effect of herd immunity.
C)  Your choice is fine,maybe you will change your mind when your child goes to college.
D)  This is not a smart choice.You could face potential arrest for not vaccinating your child per the regulations of the US government.E) C) and D)
F) A) and B)

Question 14

Which lymphocytes lack specificity for antigen and attack cancer cells and virus-infected cells?

Accepted Answer

A)  helper T cells
B)  suppressor T cells
C)  cytotoxic T cells
D)  delayed hypersensitivity T cells
E)  natural killer (NK) cellsF) C) and D)
G) B) and E)

Question 15

Autoimmune disorders are characterized by immune destruction of self tissues.The underlying basis of these disorders is:

Accepted Answer

A)  oversecretion of antibodies from memory B cells
B)  lack of immune tolerance
C)  lack of an anamnestic response
D)  overproduction of complementE) None of the above
F) All of the above

Question 16

The hinge region of an antibody has a hypervariable amino acid region where the antigenic determinant fits.

Accepted Answer

A) True 
 B)False

Question 17

The major histocompatibility complex is

Accepted Answer

A)  a set of glycoproteins,called MHC antigens,found on all body cells.
B)  a set of genes that code for MHC glycoproteins.
C)  found on the third chromosome.
D)  located in the thymus gland.
E)  All of the choices are correct.F) None of the above
G) A) and E)

Question 18

Edward Jenner's work involved

Accepted Answer

A)  inoculation of dried pus from smallpox pustules into a person to stimulate immunity.
B)  development of passive immunotherapy.
C)  development of an immunization to protect people against cowpox.
D)  immunization using a related,less pathogenic organism to give protection against a more pathogenic one.E) B) and C)
F) B) and D)

Question 19

The embryonic yolk sac,the liver,and the bone marrow are sites where

Accepted Answer

A)  immune responses to antigen occur.
B)  stem cells give rise to immature lymphocytes.
C)  antigen is filtered from the blood.
D)  antigen is filtered from tissue fluid.
E)  T lymphocytes complete maturation.F) A) and C)
G) A) and B)

Question 20

Activation of B cells occurs when antigen binds to B cell surface immunoglobulin receptors.

Accepted Answer

A) True 
 B)False

Exam 15: Host Defenses II: Specific Immunity and Immunization

Lymphocyte maturation involves

Correct AnswerverifiedShow Answer

Which of the following is a special binding substance that enhances immunogenicity and prolongs antigen retention at the injection site?

Correct AnswerverifiedShow Answer

You do not really want to get your 3 children vaccinated.Your view is why do it,when others around you will get the vaccine and end up protecting you and your children.Which is an accurate statement that your physician may provide to you in response to your challenge to vaccination?

Correct AnswerverifiedShow Answer

Which of the following is not a target for TC cells?

Correct AnswerverifiedShow Answer

Autoimmune disorders are characterized by immune destruction of self tissues.The underlying basis of these disorders is:

Correct AnswerverifiedShow Answer

The most significant cells in graft rejection are

Correct AnswerverifiedShow Answer

High titers of specific antibodies are characteristic of

Correct AnswerverifiedShow Answer

What type of cells secrete antibodies?

Correct AnswerverifiedShow Answer

Antigens that elicit allergic reactions are called

Correct AnswerverifiedShow Answer

The major histocompatibility complex is

Correct AnswerverifiedShow Answer

Class II MHC genes code for

Correct AnswerverifiedShow Answer

The embryonic yolk sac,the liver,and the bone marrow are sites where

Correct AnswerverifiedShow Answer

The hinge region of an antibody has a hypervariable amino acid region where the antigenic determinant fits.

Correct AnswerverifiedShow Answer

Each _____ fragment of an antibody molecule contains the variable regions of a heavy and light chain that folds into a groove for one epitope.

Correct AnswerverifiedShow Answer

Which lymphocytes lack specificity for antigen and attack cancer cells and virus-infected cells?

Correct AnswerverifiedShow Answer

Edward Jenner's work involved

Correct AnswerverifiedShow Answer

Activation of B cells occurs when antigen binds to B cell surface immunoglobulin receptors.

Correct AnswerverifiedShow Answer

All nucleated cells contain

Correct AnswerverifiedShow Answer

Properties of effective antigens include all of the following except

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A patient enters your clinic with a suspected helminthic infection.In support of this diagnosis,you suspect elevated levels of which antibody in the patient's serum?

Correct AnswerverifiedShow Answer

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Which of the following is not a target for T_C cells?

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