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Where does glycolysis takes place?


A) mitochondrial matrix
B) mitochondrial intermembrane space
C) mitochondrial inner membrane
D) mitochondrial membrane
E) cytosol

F) All of the above
G) C) and D)

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Which of the following statements about the electron transport chain in cell respiration is CORRECT?


A) The electron transport chain of proteins uses ATP to pump H+ across the inner mitochondria membrane against its electrochemical gradient.
B) The electron transport chain of proteins contains pores that are leaky to H+.
C) The loss in free energy of the electron initially donated by NADH is used to transport H+ across the inner mitochondrial membrane against its electrochemical gradient.
D) Electrons move from NADH to a chain of proteins with lower electronegativities.
E) The ATP synthase generates a H+ gradient across the inner mitochondrial membranE.

F) A) and E)
G) A) and C)

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In the citric acid cycle,the acetyl group is removed from acetyl CoA and attached to oxaloacetate to form


A) oxaloacetate.
B) citrate.
C) malate.
D) succinate.
E) fumaratE.

F) A) and D)
G) A) and C)

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In the equation,C6H12O6 + 6O2 \rarr 6CO2 + 6H2O,ATP and heat would be on which side of the reaction?


A) The reactants because this is an endergonic reaction.
B) The reactants because this is an exergonic reaction.
C) The products because this is an endergonic reaction.
D) It could appear on either size because this reaction is in equilibrium.
E) The products because this is an exergonic reaction.

F) A) and B)
G) A) and C)

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The enzyme responsible for converting pyruvate to acetyl CoA is called


A) hexokinase.
B) pyruvate oxidase.
C) ATP synthase.
D) pyruvate dehydrogenase.
E) peptidasE.

F) B) and C)
G) All of the above

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Enzymes are consumed in chemical reactions and must therefore be replenished.

A) True
B) False

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The process of breaking glycogen down to glucose is an example of


A) catabolism
B) catalysis
C) dehydration
D) anabolism
E) metabolism

F) C) and D)
G) B) and C)

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The reaction phosphoenolpyruvate + ADP \rarr pyruvate + ATP ( Δ\Delta G = -7.5 kcal/mole) ,


A) consumes energy.
B) is not spontaneous.
C) is an endergonic reaction.
D) requires that energy is being transferred from phosphoenolpyruvate to ADP.
E) requires that energy is being transferred from ADP to phosphoenolpyruvatE.

F) A) and D)
G) A) and E)

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Where are the protein complexes associated with the electron transport chain located?


A) mitochondrial matrix
B) mitochondrial membrane
C) mitochondrial inner membrane
D) mitochondrial intermembrane space
E) cytosol

F) C) and D)
G) All of the above

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Noncompetitive inhibitors bind the active site of an enzyme,reducing its activity and the subsequent formation of product.

A) True
B) False

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High-energy electrons from molecules of NADH and FADH2 are transferred to a chain of proteins within the electron transport chain.What is the final protein in the electron transport chain?


A) carbon dioxide
B) NAD+
C) ubiquinone
D) cytochrome c
E) oxygen

F) D) and E)
G) B) and C)

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Oxygen is an excellent final electron acceptor because of its low electronegativity.

A) True
B) False

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Glycolysis involves 10 enzyme-catalyzed steps,that can be grouped into three phases: energy investment phase,cleavage phase,and the energy liberation phase.

A) True
B) False

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In a PET scan a patient is injected with radioactively labeled glucose.Cancer cells are often in a hypoxic environment,why would this lead to an increase in glucose uptake?


A) More energy is produced from glucose in hypoxic conditions.
B) They rely more on glycolysis which is less efficient than oxidative phosphorylation.
C) They rely more on oxidative phosphorylation which is less efficient than glycolysis.
D) Enzymes function more efficiently in the absence of oxygen.
E) Because they require more oxygen to metabolize glucosE.

F) A) and B)
G) All of the above

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