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Which of the following molecules does not cross the inner membrane of the mitochondria?


A) ATP
B) acetyl-CoA
C) pyruvate
D) oxygen

E) B) and C)
F) None of the above

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Since membranes are relatively impermeable to ions,most of the protons re-enter the matrix by passing through special channels in the inner mitochondrial membrane.Because of the inward flow of protons these channels allow the synthesis of


A) ADP from ATP and Pi.
B) ATP from ADP and Pi.
C) glucose from pyruvate.
D) acetyl-CoA from pyruvate.
E) citrate from oxaloacetate and acetyl-CoA.

F) B) and C)
G) A) and D)

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The chemical 2,4 dinitrophenol (DNP) is used in the manufacturing of dyes,wood preservatives,explosives,and insect control substances,and as a photographic developer.Products containing DNP are toxic because DNP uncouples oxidative phosphorylation.In a cell exposed to DNP,how many ATP molecules would be generated per molecule of glucose?


A) 2
B) 4
C) 36
D) 38

E) C) and D)
F) B) and D)

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The oxygen utilized in cellular respiration finally shows up as


A) CO2.
B) ATP.
C) new O2.
D) H2O.
E) part of a sugar.

F) B) and D)
G) C) and D)

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The reaction,C6H6O6 + 6O2 = 6 CO2 + 6 H2O,when it occurs in living cells is known as


A) aerobic fermentation.
B) anaerobic fermentation.
C) aerobic respiration.
D) glycolysis.
E) oxidative phosphorylation.

F) C) and D)
G) C) and E)

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Pyruvate oxidation;carrier of acetyl groups.


A) ATP
B) FAD
C) G3P
D) NAD+
E) acetyl-CoA

F) A) and C)
G) B) and D)

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Which of the following statements about fermentation is false?


A) Fermentation takes place only in the absence of oxygen.
B) The recipient of hydrogen atoms is an organic molecule.
C) Water is not one of the by-products.
D) The Krebs cycle and electron transfer system do not occur.
E) Cells can only undergo one type of fermentation.

F) C) and D)
G) B) and E)

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Chief energy currency of cells;formed by chemiosmosis.


A) ATP
B) FAD
C) G3P
D) NAD+
E) acetyl-CoA

F) C) and D)
G) A) and D)

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The enzymes of the Krebs cycle are located in the


A) cytoplasm.
B) inter-membrane space of mitochondria.
C) vesicles of the ER.
D) outer membrane of the mitochondria.
E) matrix of the mitochondria.

F) B) and E)
G) C) and D)

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A biochemist wants to control the initial substrate-level phosphorylation that occurs in the tracheal cells of grasshoppers once glucose has crossed the plasma membrane.This means that he will


A) have to prevent cAMP from entering the tracheal cells.
B) have to prevent pyruvate reduction from occurring.
C) have to prevent glycolysis from occurring in the mitochondria.
D) have to prevent glycolysis from occurring in the cytoplasm.
E) have to prevent aerobic respiration in the cytoplasm.

F) B) and E)
G) B) and C)

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For further derivation of energy,aerobic cells must convert pyruvate into acetyl-CoA by stripping off a C02 molecule.This process is known as ___________.


A) decarboxylation
B) glycolysis
C) The Kreb's cycle
D) metabolism

E) B) and C)
F) A) and C)

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When ATP levels are high,oxidative pathways are inhibited,so acetyl-CoA is channeled into


A) fatty acid synthesis.
B) pyruvate formation.
C) the Krebs cycle.
D) the electron transport system.
E) NAD production.

F) D) and E)
G) B) and D)

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In the absence of oxygen,hydrogen atoms generated by glycolysis are donated to organic molecules in a process called


A) fermentation.
B) decarboxylation.
C) chemiosmosis.
D) electron transport chain reactions.
E) acetyl-CoA formation.

F) C) and D)
G) All of the above

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The decarboxylation step of oxidation of pyruvate takes place in the


A) cytoplasm.
B) Golgi body.
C) ribosome.
D) mitochondrion.
E) nucleus.

F) A) and B)
G) B) and E)

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The amino acids must be first __________ before they can be used in catabolic reactions.


A) stripped
B) proteins
C) deoxygenated
D) deaminated

E) A) and B)
F) A) and C)

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Cytochromes are respiratory proteins.Which of the following statements accurately reflects their true nature?


A) Cytochrome proteins reside free in the lung cells of all vertebrates.These molecules contain a heme group with an iron atom at its center.
B) Cytochrome proteins reside in the mitochondria and are specifically associated with the electron transport system.
C) Cytochrome proteins reside in the mitochondria and are specifically associated with the Kreb cycle.
D) Cytochrome proteins reside in the mitochondria and are specifically associated with glycolysis.

E) All of the above
F) A) and B)

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The energy released in the mitochondrial electron transport chain is used to transport protons into the


A) matrix.
B) cytoplasm.
C) ER.
D) inter-membrane space of mitochondria.
E) enzyme complex of the Krebs cyclE.

F) B) and E)
G) D) and E)

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Organisms that can manufacture their own chemical energy sources are called _____________.


A) autotrophs
B) heterotrophs
C) oligotrophs
D) chemotrophs

E) A) and B)
F) A) and C)

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All of the following are the end products of glycolysis except


A) pyruvate.
B) ATP.
C) NADH.
D) NAD+.
E) energy.

F) A) and C)
G) B) and E)

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Intermediate in glycolysis;finally oxidized to pyruvate.


A) ATP
B) FAD
C) G3P
D) NAD+
E) acetyl-CoA

F) A) and C)
G) A) and E)

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