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The surface defenses of the body consist of the ______ and the mucous membranes lining the digestive and respiratory tracts.


A) bone marrow
B) skin
C) T-cells
D) lymphocytes

E) A) and B)
F) B) and D)

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Individuals who lack antigens on their red blood cell surfaces are more likely to be


A) A,Rh+.
B) B,Rh+.
C) AB,Rh-.
D) O,Rh-.
E) O,Rh+.

F) C) and E)
G) B) and D)

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Referring to the figure,which statement is false? Referring to the figure,which statement is false?   A) Cytokines are produced in both diagrams. B) Antigens are produced in both diagrams. C) Naïve cells are involved in diagram I. D) The humoral response represents diagram II.


A) Cytokines are produced in both diagrams.
B) Antigens are produced in both diagrams.
C) Naïve cells are involved in diagram I.
D) The humoral response represents diagram II.

E) All of the above
F) A) and D)

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_________ are the source of antibody-producing cells.


A) B cells
B) Macrophages
C) Plasma cells
D) T cells
E) Monocytes

F) A) and B)
G) C) and D)

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Select the incorrect statement regarding the class of proteins,known as interferons,that play a key role in body defenses.


A) There are three types of interferons,alpha,beta,and gammA.
B) All cells of the body produce all three types of interferon.
C) The secretion of gamma interferon is an immunological defense against infections and cancer.
D) All interferons are polypeptides.
E) Interferons are messengers that protect normal cells in the areas of infected cells from becoming infected.

F) None of the above
G) C) and D)

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__________ diseases are those abnormal conditions in which the body's defensive cells fail to make the self versus the nonself distinction correctly,and attack the body's own tissues.


A) Septic
B) Nondiscrete
C) Autoimmune
D) Cancerous

E) All of the above
F) A) and B)

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The ability of a vertebrate to generate millions of different lymphocytes is a result of its DNA undergoing


A) DNA rearrangement.
B) DNA reestablishment.
C) clonal variability.
D) instructional variation.
E) gene cloning.

F) All of the above
G) A) and B)

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The development of T cells in the thymus is overseen by


A) suppressor cells.
B) cytotoxic cells.
C) mediator cells.
D) inducer cells.
E) helper cells.

F) C) and D)
G) B) and C)

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Which of the following is true regarding cytokines?


A) Cytokines are secreted by TH cells and bind to receptors.
B) Cytokines are immune cells involved in producing antibodies.
C) Cytokines are secreted in high concentrations during infection.
D) Cytokines bind to intracellular receptors.
E) Cytokines protect in the attack of pathogens by phagocytosis.

F) A) and B)
G) All of the above

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_________ are macrophage precursor cells.


A) B cells
B) Macrophages
C) Plasma cells
D) T cells
E) Monocytes

F) A) and B)
G) D) and E)

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All of the following are types of leukocytes except


A) neutrophils.
B) eosinophils and basophils.
C) monocytes.
D) T and B cells.
E) erythrocytes.

F) A) and C)
G) None of the above

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The cellular defenses of vertebrates are complemented by a very effective chemical defense called the _________ system.


A) autoimmune
B) relational
C) lymphatic
D) complement

E) C) and D)
F) A) and D)

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If different types of blood are mixed together because different antibodies exist for the ABO and Rh factor antigens on the surface of red blood cells,


A) an autoimmune reaction will occur.
B) an infection will occur.
C) an agglutination reaction will occur.
D) an inflammatory reaction will occur.
E) a temperature response will occur.

F) C) and D)
G) A) and D)

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Lymphocyte receptors are encoded by genes that are assembled by _______ rearrangement And mutation.


A) histochemical
B) reversible
C) gametic
D) DNA

E) A) and B)
F) A) and C)

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Immunity gained by the transfer of antibodies across the placental barrier is called


A) passive immunity.
B) acquired immunity.
C) humoral immunity.
D) cell-mediated immunity.
E) auto immunity.

F) A) and B)
G) A) and C)

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_________ produce specific antibodies.


A) B cells
B) Macrophages
C) Plasma cells
D) T cells
E) Monocytes

F) A) and B)
G) A) and C)

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Which of the following is not a class of immunoglobin?


A) IgM
B) IgD
C) IgC
D) IgG
E) IgA

F) A) and E)
G) B) and C)

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Which of the following is not part of the inflammatory response?


A) Histamine and other chemicals are released,which produce redness,warmth,and edemA.
B) Neutrophils,monocytes,and macrophages attack the invading microbes and contribute to the pus.
C) Antibodies and interferons are produced against the antigens.
D) Invading agent causes the release of pyrogens,which produce a fever.

E) A) and B)
F) A) and C)

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The human immunodeficiency virus mounts a direct attack on TH cells by recognizing the _______ surface proteins associated with these cells.


A) Fc
B) CD4
C) epitope
D) cytokine

E) B) and C)
F) B) and D)

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A friend tells you the following story."My aunt just received a heart transplant.Her doctors warned us that her body might reject the tissue.I just can't understand how that could happen as human hearts are made of the same tissues,aren't they?" Your correct response should be


A) "Yes,all human hearts are made of cardiac muscles."
B) "Yes,all human hearts are made of cardiac muscles,except some humans have different tissues inside their hearts and this could lead to a tissue rejection by the recipient."
C) "Yes,all human hearts are made of cardiac muscles.As far as the rejection of tissues goes,your aunt might have different antibodies than did the donor,which could lead to a rejection."
D) "Yes,all human hearts are made of cardiac muscles.However,your aunt might have been given some type of drug during the transplant operation that might cause tissue rejection.You can never be too careful in a hospital,you know."
E) "Yes,all human hearts are made of cardiac muscles.As far as the rejection issue,everyone has different MHC proteins on their tissues.Your aunt's immune system recognizes the 'self' tissues but can cause tissue rejection because of the 'nonself' tissue in her body having different MHC proteins."

F) None of the above
G) C) and D)

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