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Which of the following statements is NOT correct regarding the motor units and their activation?


A) A motor unit in muscles of gross movement can have thousands of muscle cells.
B) All muscle fibers in a single motor unit are of the same fiber type.
C) A weak contractile stimulus activates fast-twitch motor units.
D) The metabolic capacity of muscle fibers within a motor unit can be altered.
E) At its peak intensity, a contractile stimulus will activate muscle fibers that are easily fatigued.

F) C) and E)
G) C) and D)

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Which fibers fatigue sooner?


A) fast-twitch fibers
B) slow-twitch fibers

C) A) and B)
D) undefined

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The reductions in muscle force generation at lengths different from optimal are a result of a(n)________.

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decrease i...

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The action potential traveling along the t-tubule is detected by the


A) ryanodine receptor.
B) dihydropyridine (DHP) receptor (L-type calcium channel) .
C) acetylcholine receptor.
D) Ca2+ ATPase.

E) A) and B)
F) A) and C)

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Skeletal muscle cells are usually attached to bone by


A) fascicles.
B) ligaments.
C) tendons.
D) flexors.

E) B) and C)
F) All of the above

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Factors playing a role in fatigue can be classified into 2 categories.Define those two categories and provide an example of each.

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Central fatigue,peripheral fatigue.Centr...

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The nervous system avoids muscle fatigue during submaximal contraction by


A) always recruiting slow-twitch motor units.
B) asynchronous recruitment.
C) synchronous recruitment.
D) always recruiting fast-twitch motor units.

E) A) and C)
F) None of the above

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A(n)________ contraction describes the opening of stretch-activated channels in smooth muscle cells in response to a distortion of the cell membrane that is commonly observed in ________.

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myogenic,b...

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Match from the following list. -The structures that serve as the attachment site for the thin filaments and mark the boundaries for one sarcomere.


A) A band
B) I band
C) Z disk
D) H zone
E) M line

F) A) and E)
G) A) and D)

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Sketch a graph of the length-tension relationship in a contracting skeletal muscle,and explain its shape in terms of events in the sarcomere.

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Smooth muscle fibers can sustain a contraction without fatigue by allowing dephosphorylated myosin to remain attached to actin in what is called the ________.

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In the lever system that characterizes the interaction between bones and muscle,the bones act as the ________ whereas the joints form the ________.


A) lever, fulcrums
B) fulcrum, levers
C) lever, pulleys
D) fulcrum, pulleys

E) C) and D)
F) A) and B)

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This protein is activated by the Ca2+-calmodulin complex to phosphorylate the myosin light chain protein.


A) tropomyosin
B) myosin heavy chain
C) myosin light chain kinase
D) myosin light chain phosphatase

E) A) and B)
F) A) and C)

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Compare and contrast the structural and functional differences between single-unit and multi-unit smooth muscle fibers,particularly in regard to their ability to vary their force of contraction.

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Single-unit characteristics: all smooth ...

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Store-operated calcium channels open in response to ________.

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depleted i...

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Groups of adjacent fibers bundled together into units are called ________.These bundles are surrounded by the proteins ________ and elastin as well as ________ that deliver nutrients to the muscle cells.

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fascicles;...

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Which of the following would cause the crossbridge to transition from a high force state to a low force state?


A) increasing myosin ATPase activity
B) increasing intracellular calcium
C) decreasing intracellular calcium
D) energizing the myosin head
E) decreasing myosin ATPase activity

F) C) and E)
G) A) and E)

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A motor unit consists of


A) one neuron and all the skeletal muscle fibers it controls.
B) one skeletal muscle fiber and all the neurons that control that fiber.
C) one skeletal muscle fiber and the neuron that controls that fiber.
D) one axon terminal branch and the myofibrils it controls.

E) A) and D)
F) All of the above

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Fatigue that occurs in response to extended submaximal exertion is usually due to ________ whereas fatigue to a short duration of maximal exertion involves ________.

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glycogen depletion,e...

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The brief period of time between the beginning of the action potential in the muscle and the beginning of contraction is referred to as the


A) refractory period.
B) latent period.
C) relaxation phase.
D) depolarization period.
E) repolarization period.

F) A) and D)
G) A) and C)

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