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Leukocytes responsible for killing intracellular viruses are


A) Fixed Macrophages
B) Basophils
C) Granulocytes
D) Natural Killer cells

E) A) and C)
F) B) and C)

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Complement


A) system consists of over 20 proteins that function in a cascade-like manner
B) activation results in the onset of fever
C) pathway involves factors B, D and P
D) all of the above

E) A) and B)
F) A) and C)

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Bacteria that resist digestion by phagocytes use all of the following mechanisms except


A) produce capsule that can resist lysosomal digestion
B) block chemokines from reaching phagocytes
C) form parasitophorous vacuoles
D) produce streptolysisin and leukocidin

E) None of the above
F) B) and C)

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A leukocyte-endogenous mediator


A) elevates body temperature
B) lowers the plasma iron concentration
C) decreases the host's metabolic rate
D) two of the above

E) B) and D)
F) All of the above

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Exogenous and endogenous __________ are fever causing substances


A) prostraglandins
B) pyrogens
C) cytokines
D) bradykines

E) A) and D)
F) A) and C)

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What non-specific immune component is directly responsible for the lysis of invading microorganisms?


A) chemotaxis
B) membrane attack complex
C) opsonin
D) chronic inflammation

E) C) and D)
F) A) and D)

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Toll-like receptors can distinguish between


A) nonspecific and specific immune responses
B) gram-negative and gram-positive bacteria
C) bacteria versus viruses
D) two of the above

E) C) and D)
F) None of the above

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A multilobed lymphatic organ that functions to process lymphocytes known as T cells and release them into the blood is called:


A) tonsil
B) trachea
C) thymus gland
D) salivary gland

E) B) and D)
F) A) and D)

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Acute phase response proteins


A) include C-reactive protein (CRP) and mannose-binding protein (MBP)
B) bind to and coat the surface of the infectious agent
C) destroy abnormal cells
D) increase resistance of cells to viral infection

E) B) and D)
F) B) and C)

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What collection of lymphoid tissue,found in the ileum of the small intestine,is comprised of unencapsulated regions filled with lymphocytes,called lymphoid nodules?


A) gut-associated lymphatic tissues
B) mucosa-associated lymphatic tissues
C) phagosomes
D) tonsils

E) B) and D)
F) All of the above

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During inflammation,permeable capillary walls allow accumulation of fluids near injured cells causing which of the following?


A) calor
B) diapedesis
C) edema
D) blood clotting

E) None of the above
F) A) and B)

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All of the following are components of the nonspecific host defenses except


A) fever
B) mucus
C) antibodies
D) interferon

E) A) and C)
F) A) and B)

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Toll-like receptors


A) come from outside the body and stimulate a cytokine
B) act nonspecifically to cause cell killing
C) are a set of receptors that when activated produce a membrane attack complex
D) recognize molecular patterns unique to pathogens

E) A) and C)
F) A) and B)

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Which of the following does not partake in the process of phagocytosis?


A) chemotaxis
B) granulation
C) adherence
D) ingestion

E) All of the above
F) B) and C)

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Physical barriers of nonspecific defenses


A) include both the cells that line the body surfaces and the chemicals they secrete
B) include phagocytes and interferon
C) respond to antigens by making thousands of different antibodies
D) are part of the host cellular defenses

E) All of the above
F) B) and C)

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Residual body


A) is the remains of parasitic worms killed extracellularly
B) consists of a thin layer of cells that secrete mucus
C) prevents adherence of a phagocyte and a bacterium
D) is material that remains in a phagolysosome after digestion of a microbe

E) B) and C)
F) All of the above

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Blood contains cells including all of the following except


A) red blood cells
B) plasma
C) platelets
D) lymphocytes

E) All of the above
F) A) and D)

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A pocket of tissue that surrounds and walls off the inflammatory agent is called a


A) granuloma
B) edema
C) fibroblast
D) pyrogen

E) All of the above
F) None of the above

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The lymphatic system does all of the following except


A) carries plasma to tissue
B) transports digested fats to the cardiovascular system
C) drains excess fluid from space between cells
D) allows for the circulation of cellular defenses

E) None of the above
F) A) and B)

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Which of the following proteins activate complement,enhance inflammation and stimulate macrophages to undergo chemotaxis?


A) antiviral proteins
B) exogenous pyrogens
C) leukocidins
D) acute phase proteins

E) None of the above
F) A) and C)

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