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Muscular dystrophy is characterized by


A) chronic muscle pain.
B) decreased size of muscle fibers.
C) spastic contractions of muscles.
D) replacement of muscle cells by connective tissue.
E) hypertrophy of muscle tissue.

F) None of the above
G) A) and E)

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A stimulus either causes an action potential or it doesn't. This is called


A) an all-or-none response.
B) a graded response.
C) a latent period response.
D) a relative refractory response.
E) an arbitrary response.

F) A) and E)
G) All of the above

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What is tropomyosin?


A) a protein found along the groove of the F-actin double helix
B) a T tubule and two adjacent terminal cisternae
C) the combination of myosin heads with active sites on actin molecules
D) the movement of myosin head while attached to actin myofilament
E) after exercise, the oxygen taken in that exceeds the oxygen required for resting metabolism

F) None of the above
G) A) and E)

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What is an oxygen deficit?


A) a protein found along the groove of the F-actin double helix
B) a T tubule and two adjacent terminal cisternae
C) the combination of myosin heads with active sites on actin molecules
D) the movement of myosin head while attached to actin myofilament
E) after exercise, the oxygen taken in that exceeds the oxygen required for resting metabolism

F) A) and E)
G) All of the above

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A toxin released by the anaerobic bacterium Clostridium botulinum causes the food-borne illness known as botulism, which inhibits the release of ACh at the neuromuscular junction. What effect does this have on the person?


A) It causes flaccid paralysis, and if it affects the respiratory muscles, can result in death.
B) It disrupts the balance between ACh and acetylcholinesterase, leading to spastic contractions.
C) The brain compensates by producing more ACh, limiting the illness to only a few hours.
D) The jaws are most affected, and it results in "lockjaw."
E) Problems only result when the individual has low immunity.

F) A) and E)
G) C) and D)

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Arrange these structures as they participate in excitation-contraction.


A) T tubules, sarcolemma, calcium ions, sarcoplasmic reticulum
B) calcium ions, T tubules, sarcolemma, sarcoplasmic reticulum
C) sarcolemma, T tubules, sarcoplasmic reticulum, calcium ions
D) sarcoplasmic reticulum, calcium ions, T tubules, sarcolemma
E) sarcolemma, sarcoplasmic reticulum, calcium ions, T tubules

F) A) and E)
G) A) and C)

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  -The figure illustrates a detailed drawing of the neuromuscular junction. What does  E  represent? A)  synaptic vesicles B)  synaptic cleft C)  sarcolemma D)  presynaptic terminal E)  postsynaptic membrane -The figure illustrates a detailed drawing of the neuromuscular junction. What does "E" represent?


A) synaptic vesicles
B) synaptic cleft
C) sarcolemma
D) presynaptic terminal
E) postsynaptic membrane

F) D) and E)
G) B) and D)

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The model that describes the contraction of the muscle is called the


A) contraction cycle.
B) power stroke.
C) sliding filament model.
D) slipping fibril mechanism.
E) paddle model.

F) C) and D)
G) B) and E)

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  -The figure illustrates a detailed drawing of the neuromuscular junction. What does  A  represent? A)  synaptic vesicles B)  synaptic cleft C)  sarcolemma D)  presynaptic terminal E)  postsynaptic membrane -The figure illustrates a detailed drawing of the neuromuscular junction. What does "A" represent?


A) synaptic vesicles
B) synaptic cleft
C) sarcolemma
D) presynaptic terminal
E) postsynaptic membrane

F) A) and B)
G) All of the above

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Which of the following causes an unequal ion concentration across the resting plasma membrane?


A) the functioning of the sodium-chloride pump
B) negatively charged proteins do not readily diffuse across the plasma membrane
C) the attraction of chloride ions to other intracellular anions
D) the repulsion of potassium ions by the intracellular anions
E) the attraction of sodium ions to chloride ions

F) C) and D)
G) All of the above

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Epimysium


A) surrounds individual muscles.
B) separates muscle fibers.
C) connects muscles to bone.
D) is a type of muscle tissue.
E) is a type of nerve tissue.

F) B) and D)
G) A) and B)

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The type of neurotransmitter or hormone that binds to receptors on smooth muscle plasma membranes determines the response of the muscle.

A) True
B) False

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Channels that open or close in response to changes in the electrical charge or voltage across the plasma membrane are called


A) ligand-gated ion channels.
B) leak ion channels.
C) relegated ion channels.
D) voltage-gated ion channels.
E) obligated ion channels.

F) C) and D)
G) B) and E)

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A fasciculus


A) is a bundle of reticular fibers.
B) is surrounded by perimysium.
C) is only found in smooth muscle.
D) possesses an external lamina.
E) is a bundle of collagen fibers.

F) B) and E)
G) B) and C)

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Skeletal muscle fibers


A) possess striations.
B) can contract but are not extensible or excitable.
C) do not require nerve innervation to contract.
D) increase dramatically in number after birth.
E) are found in the walls of the stomach.

F) A) and E)
G) B) and C)

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In order for the excitation-contraction coupling to occur, the production of an action potential must occur within the ______ of a muscle fiber.


A) contraction
B) sarcolemma
C) junction

D) A) and B)
E) A) and C)

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A proper definition of muscle tone is


A) constant tension produced by muscles for long periods of time.
B) a feeling of well-being following exercise.
C) the ability of a muscle to maintain a contraction against an outside force.
D) muscles contracting together.
E) warm-up of muscle tissue.

F) B) and C)
G) A) and E)

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Select the term that does not belong with the others.


A) muscle atrophy
B) immobilization
C) decrease in number of myofibrils
D) loss of nerve stimulation
E) increased vascularity

F) C) and E)
G) None of the above

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In smooth muscle, cross-bridging occurs due to


A) calcium binding to troponin.
B) calcium binding to calmodulin.
C) myosin kinase adding a phosphate to myosin heads.
D) both calcium binding to troponin and calmodulin.
E) both calcium binding to calmodulin and myosin kinase adding a phosphate to myosin heads.

F) B) and C)
G) All of the above

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Endomysium is a delicate network of loose connective tissue that


A) surrounds each muscle fiber.
B) forms a sheath around a fasciculus.
C) is composed of elastic fibers.
D) separates individual muscles.
E) penetrates muscle fibers.

F) A) and B)
G) C) and D)

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