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The analysis of the nitrogenous bases of the nucleic acid of a newly discovered virus showed 20% adenine, 40% guanine, 10% thymine, and 30% cytosine. The viral nucleic acid is most likely


A) double-stranded DNA.
B) double-stranded RNA.
C) single-stranded RNA.
D) single-stranded DNA.

E) B) and C)
F) A) and D)

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DNA polymerase III


A) is needed for adding nucleotides during mRNA synthesis.
B) synthesizes new DNA only in the 5'to 3'direction.
C) cannot add nucleotides to the lagging strand.
D) synthesizes an RNA primer.
E) All of these choices are correct.

F) A) and B)
G) B) and E)

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Which of the following is not true of an organism's genotype?


A) The genotype is inherited.
B) The genotype is made up of structural genes coding for proteins.
C) The genotype includes genes coding for RNA.
D) The genotype includes regulatory genes controlling gene expression.
E) The genotype includes the expressed traits governed by the genes.

F) A) and B)
G) B) and E)

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Transcription occurs in the nucleus or at the nucleoid.

A) True
B) False

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A sequence of bases within a gene that will be transcribed, but removed from the transcript prior to translation is a/an


A) promoter.
B) operator.
C) operon.
D) exon.
E) intron.

F) A) and B)
G) A) and D)

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Which of the following is not true of conjugation?


A) involves direct contact between cells
B) transfers genes for drug resistance
C) transfers genes for enzymes and adherence molecules
D) transfers genes for a polysaccharide capsule
E) The donor retains a copy of the transferred genes.

F) A) and C)
G) A) and D)

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Synthesis of an inducible enzyme requires


A) repressor alone bound to operator.
B) substrate bound to repressor.
C) substrate bound to promoter.
D) corepressor and repressor binding to operator.

E) A) and B)
F) All of the above

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Base pairs in DNA are held together by _____ bonds.


A) peptide
B) nonpolar covalent
C) polar covalent
D) hydrogen
E) sulfhydryl

F) B) and E)
G) A) and B)

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In Griffith's experiments with Streptococcus pneumoniae, rough nonencapsulated Streptococci were converted into smooth encapsulated Streptococci in the presence of the heat-killed smooth encapsulated Streptococci. What is the term that describes this process?


A) transduction
B) conjugation
C) transformation
D) cloning

E) C) and D)
F) A) and C)

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Short interfering RNAs affect gene expression in eukaryotes by


A) blocking replication of certain genes.
B) blocking transcription of certain genes.
C) binding to mRNAs and preventing translation.
D) binding to ribosomes, preventing the two subunits from joining.

E) None of the above
F) A) and B)

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Each _____ is a specific segment of the DNA with the code for production of one functional product.


A) intron
B) exon
C) gene
D) operator
E) triplet

F) D) and E)
G) A) and D)

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Hfr transfer involves all of the following except


A) gene integration into the bacterial chromosome.
B) plid gene transfer.
C) F factor is part of the F+ donor chromosome.
D) high frequency transfer.
E) a pilus connection between F+ and F- cells.

F) A) and C)
G) C) and D)

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Each nucleotide is composed of


A) one phosphate, one nitrogenous base, one sugar.
B) one phosphate, one nitrogenous base, two sugars.
C) two phosphates, one nitrogenous base, one sugar.
D) two phosphates, one nitrogenous base, two sugars.
E) one phosphate, two nitrogenous bases, one sugar.

F) A) and B)
G) B) and D)

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A mutation that changes a normal codon to a stop codon is called a


A) point mutation.
B) silent mutation.
C) back mutation.
D) missense mutation.
E) nonsense mutation.

F) All of the above
G) C) and E)

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The different types of nucleic acids found in viruses include all of the following except


A) double-stranded DNA.
B) single-stranded DNA.
C) double-stranded RNA.
D) single-stranded RNA.
E) There are no exceptions here. Each of these types may be found in viruses.

F) All of the above
G) A) and E)

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What molecule is synthesized as a copy of a gene from the DNA template strand?


A) ribosomal RNA
B) messenger RNA
C) transfer RNA
D) primer RNA
E) ribozymes

F) B) and C)
G) A) and E)

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Which of the following is not true of the prokaryotic ribosome?


A) Prokaryotic ribosomes are 70S.
B) A prokaryotic ribosome has a peptide P) site.
C) A prokaryotic ribosome has an exit E) site.
D) The small subunit provides the enzymes for making peptide bonds.
E) The prokaryotic ribosome has an amino acyl A) site.

F) B) and D)
G) A) and D)

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The enzyme that can proofreads replicating DNA, detects incorrect bases, excises them, and correctly replaces them is


A) DNA ligase.
B) DNA polymerase.
C) DNA helicase.
D) DNA gyrase.
E) primase.

F) A) and D)
G) D) and E)

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In bacteria, initiator tRNA carries formyl methionine.

A) True
B) False

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Gene regulation can involve a protein repressor that blocks _____ from initiating transcription.


A) DNA polymerase I
B) DNA polymerase III
C) RNA polymerase
D) mRNA
E) rRNA

F) A) and B)
G) B) and E)

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